I have a love/hate relationship with quotes in pics. They can be a lot of fun and also send a pretty pointed message. I use imrflip.com which allows me to use my own pics.
The strange thing is my Twitter feed seems to be inundated with the pics. They draw my attention (which can be good or bad), but they rarely lead to conversations. Basically, they act like billboards which is a one-way communication tool. That hardly meets the social aspect of social media.
I guess I would argue that we should use them sparingly, and hopefully as part of a conversation we are having. One tweet stands are so empty.